We advise healthcare innovators on the regulatory, reimbursement, and adoption pathways between discovery and the market.

Getting healthcare
innovation to patients.

By Jonathan Ketcham

Selected clients

✦ Founder profile

Healthcare strategy grounded in economics, policy, and market reality

Jonathan Ketcham brings three decades of experience in healthcare economics research, teaching, and advising, with collaborations across government, industry, and academia.

As a distinguished professor at Arizona State University and former Chief Healthcare Economist at the White House Council of Economic Advisers, he has advised on healthcare economic policy across the entire executive branch of the US government, including CMS, FDA, NIH, and ARPA-H.

Margin Health brings that experience into focused advisory work for healthcare innovators navigating regulatory strategy, reimbursement, evidence generation, and market adoption.

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Years of healthcare economics experience across research, teaching, consulting, and policy advisory.

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Years of healthcare economics experience across research, teaching, consulting, and policy advisory.

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Years of healthcare economics experience across research, teaching, consulting, and policy advisory.

Turning healthcare evidence into market access.

Turning healthcare evidence into market access.

✦ Services

The scope of our healthcare advisory practice

We help healthcare innovators navigate regulatory pathways, reimbursement strategy, market adoption, and economic evidence, from clinical validation to commercial deployment.

The scope of our healthcare advisory practice

We help healthcare innovators navigate regulatory pathways, reimbursement strategy, market adoption, and economic evidence, from clinical validation to commercial deployment.

Regulatory Strategy

FDA Pathways

• Federal Review • Regulatory Navigation

FDA clearance and approval pathways, regulatory economics, and strategic navigation of federal agency review processes for healthcare innovations.

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Market Adoption

CMS Policy

• Payer Strategy • Sustainable Reimbursement

From clinical validation to commercial and operational deployment - market entry strategy, provider adoption, and health system integration.

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Reimbursement & Coverage

Adoption

• Integration • Scale

CMS payment policy, payer dynamics, and coverage determination strategy - ensuring clinical value translates into sustainable reimbursement.

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Healthcare Economics

Evidence

• Economics • Policy

Empirical methods, evidence synthesis, and economic modeling grounded in peer-reviewed research and two decades of federal advisory experience.

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Regulatory Strategy

FDA Pathways

• Federal Review • Regulatory Navigation

FDA clearance and approval pathways, regulatory economics, and strategic navigation of federal agency review processes for healthcare innovations.

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Market Adoption

CMS Policy

• Payer Strategy • Sustainable Reimbursement

From clinical validation to commercial and operational deployment - market entry strategy, provider adoption, and health system integration.

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Reimbursement & Coverage

Adoption

• Integration • Scale

CMS payment policy, payer dynamics, and coverage determination strategy - ensuring clinical value translates into sustainable reimbursement.

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Healthcare Economics

Evidence

• Economics • Policy

Empirical methods, evidence synthesis, and economic modeling grounded in peer-reviewed research and two decades of federal advisory experience.

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✦ Founder profile

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Jonathan
Ketcham
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Jonathan
Ketcham

THREE DECADES OF HEALTHCARE ECONOMICS

Jonathan earned his PhD from Wharton and served as Chief Healthcare Economist in the Executive Office of the President, advising on healthcare economic policy across the entire executive branch of the US government, including the HHS agencies FDA, CMS, NIH, and ARPA-H. He has also served as principal economist on Amazon’s employee benefits team. His advisory work is built on three decades of peer-reviewed econometrics research.

The experience behind the advisory practice

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FEDERAL HEALTHCARE POLICY & REGULATORY ECONOMICS

2025-2026

White House Council of Economic Advisers • FDA, CMS, NIH & ARPA-H

Jonathan Ketcham served as Chief Healthcare Economist at the White House Council of Economic Advisers, advising on healthcare economic policy across HHS and its operating divisions, including the FDA, CMS, NIH, and ARPA-H.

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HEALTHCARE ECONOMICS & MARKET DESIGN

2005-Present

Arizona State University • W. P. Carey School of Business

As the Earl G. and Gladys C. Davis Distinguished Research Professor in Business at ASU, Ketcham’s work sits at the intersection of health economics, consumer behavior, and public policy. His research uses causal-inference methods and large-scale real-world data to study how incentives, information, and institutional design influence decisions by payers, providers, and patients.

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INDUSTRY ADVISORY & COMMERCIAL HEALTHCARE STRATEGY

20+ years

Amazon, CMS, Pfizer, Banner Health, CVS Caremark & others

Ketcham has more than two decades of healthcare economics experience across research, teaching, and consulting. His work has touched pharmaceutical strategy, pharmacy benefit managers, health insurance, consumer and physician decision-making, hospital pricing, provider incentives, payment methods, employee benefits, and valuation of health outcomes.

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MARGIN HEALTH REGULATORY, REIMBURSEMENT & ADOPTION PATHWAYS

2026–Present

Founder • Healthcare Advisory

Margin Health helps leaders across private industry, government, and financial markets navigate the regulatory, reimbursement, and adoption pathways that turn healthcare innovation into operational and commercial deployment. The firm is positioned for healthcare innovators who need strategy grounded in evidence, economics, and policy reality.

✦ Testimonials

Words That Matter - Real Experiences from Real Collaborations

“Jonathan understands something: great technology only creates value if it can be adopted in the real world. His experience spanning the White House, academia, Amazon, and healthcare economics gives him a unique perspective on how new technologies move through policy, procurement, reimbursement, and institutional decision making."

Ehsan Agahi

Executive Chairman of Illumisoft

“Jonathan understands something: great technology only creates value if it can be adopted in the real world. His experience spanning the White House, academia, Amazon, and healthcare economics gives him a unique perspective on how new technologies move through policy, procurement, reimbursement, and institutional decision making."

Ehsan Agahi

Executive Chairman of Illumisoft

“Jonathan understands something: great technology only creates value if it can be adopted in the real world. His experience spanning the White House, academia, Amazon, and healthcare economics gives him a unique perspective on how new technologies move through policy, procurement, reimbursement, and institutional decision making."

Ehsan Agahi

Executive Chairman of Illumisoft

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Years of healthcare economics experience across research, teaching, consulting, and policy advisory

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✦ Research and publications

The research behind the advice

Margin Health is grounded in rigorous, peer-reviewed research.

As a distinguished professor at Arizona State University and former Chief Healthcare Economist at the White House Council of Economic Advisers, he has advised on healthcare economic policy across HHS divisions including FDA, CMS, NIH, and ARPA-H.

One publication is featured for now — more coming soon.

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LET’S TURN HEALTHCARE EVIDENCE INTO MARKET STRATEGY.

Location

Phoenix | Telluride